Proteomics Facility
The CGP Proteomics Facility combines in-depth expertise with state-of-the-art equipment for the identification and characterisation of proteins and metabolites present in cells, tissues and body fluids under different conditions, such as health and disease states. Proteins are the ultimate mediators of essentially all cellular processes and constitute the vast majority of therapeutic drug targets. Thus, the systematic analysis of proteins, especially their patterns of expression, interactions and modifications, is critical for defining key cellular processes in molecular detail. Metabolites and their changing composition provide important information on how these processes are functioning and are critical to understanding the impact of changes to disease or physiological states.
In addition to in-house research, the Facility also provides resources for outside investigators, undertakes collaborations and provides a contract service for academics and commercial users.
This laboratory provides the scientific community an opportunity to
make use of recent developments in techniques and instrumentation for
analysis and identification of proteins and metabolites. Our area of
work includes the large scale purification of proteins from recombinant
or biofluidic sources, the analytical fractionation of biochemical
compounds and peptides, the analysis and comparison of proteomes,
identification of proteins in protein spots/bands by mass spectrometry,
analysis of expressed proteins for quantitative studies and analysis of
proteins for post-translational modifications and identification of
metabolites and small molecules.
About Us
Associate Professor Dave Greenwood’s interests in both protein science and small
molecules brings together two areas where mass spectrometry is
increasingly valued as a key technology for identification and
characterisation. Dave is a Senior Scientist at the Plant & Food
Research CRI as well as having a part-time position at the School of
Biological Sciences to oversee the strategic development of proteomics
in the CGP.
Dr Martin Middleditch has worked in the area of mass spectrometry in various countries for over fifteen years, in contract research organizations, small biotech firms and universities. His experience has been gained in fields such as drug discovery and metabolism, plant biochemistry and quantitative proteomics.
Collectively the staff in the Proteomics Facility of the CGP have over 30 years of combined expertise in the field of mass spectrometry.
Contact Us
Martin MiddleditchBiochemistry & Molecular Biology Group
Thomas Building , Level 2, Room 285
3 Symonds Street, City Campus
Phone: +64-9-373-7599 x87612 (office) or x87540 (lab)
Fax: +64-9-373-7668
Associate Professor David Greenwood
Biochemistry & Molecular Biology Group
Thomas Building , Level 2, Room 285
3 Symonds Street, City Campus
Phone: +64-9-373-7599 x86631 (office) or x87540 (lab)
Fax: +64-9-373-7668
Location
Room 285, Level 2
Thomas Building
School of Biological Sciences
University of Auckland
Tel. +64-9-373 7599 ext 87540
Directors
Professor Garth J.S. CooperBiochemistry & Molecular Biology Group
Thomas Building , Level 4, Room 450
3 Symonds Street, City Campus
Phone: +64-9-373-7599 ext 87239
FAX: +64-9-373-7045
Associate Professor David Greenwood
Biochemistry & Molecular Biology Group
Thomas Building , Level 2, Room 285
3 Symonds Street, City Campus
Phone: +64-9-373-7599 ext 86631 (office) 87540 (lab)
Fax: +64-9-373-7668
A brochure is available outlining all of the services that we offer and a service request form is available as either an MS Word file or as an Adobe PDF file.